Viral HIV Vaccine Gives Durable Protection Against ‘Death Star’ Strain
Among HIV researchers, one seemingly indestructible HIV-like strain has earned the nickname “death star.” That’s due to the strain’s reputation for killing off hopes for potential vaccines and immunotherapies that could prevent the disease.
Developing an HIV vaccine that protects long-term with a single dose is an important goal, especially in places where medical resources can be scarce, anti-retroviral drugs may be unavailable, and the risk of mother-to-infant transmission of HIV can be high.
Conventional vaccine approaches typically use a piece of virus or other immunogen to activate an immune system response. Because HIV replicates and changes so quickly, that approach has proven challenging. Farzan’s approach uses a safe virus to fight the dangerous one, and relies on muscle cells rather than immune cells to generate protective agents.
Story Source & Image Source: Science Daily
Originally written by: Scripps Research Institute
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