New Immunotherapy Shows Promise Against Brain Tumors in Mice
For the first time, scientists have shown that a new type of immunotherapy can reach and treat brain cancer from the bloodstream in mice. The nano-immunotherapy stopped brain tumor cells multiplying and increased survival.
Checkpoint inhibitors are drugs that help the immune system fight cancer. In the new immunotherapy, the drugs can remove a mechanism that enables the brain tumor to withstand attack from cancer-killing cells.
Using drugs that can treat the brain systemically — that is, by using the bloodstream to deliver them — would be an advantage over treatments that only work when doctors inject them directly into brain tissue. The new study is also the first to describe an immunotherapy that can stimulate immune systems both throughout the body and local to the tumor in mice.