Decreased Organ Functions after Mild to Moderate COVID-19 infections, a study shows
In a recent study published in the European Heart Journal, intermediate-term organ-specific functions was shown affected in mild to moderate SARS-CoV-2 infected non-hospitalized individuals in Hamburg, Germany. Four hundred and forty-three individuals, aged 45–74 years old were included in this cross-sectional study, against matched subjects from an ongoing, prospective, population-based cohort study. Participants were examined in median 9.6 months after the first positive SARS-CoV-2 test. Results showed a mild to moderate course of SARS-CoV-2 infection is associated with subsequent signs of subclinical multi-organ affection. Organ specific findings showed decreased lung volume, increased airway resistance in terms of the respiratory system functions. Decreased left ventricular ejection fraction, decreased right ventricular function, increased high-sensitivity troponin, and increased N-terminal pro-B-type natriuretic peptide was found in the cardiac assessments. Increased sign of prior deep vein thrombosis, and decreased glomerular filtertaion rate was found as well in the vascular and renal system assessments. Authors concluded that systematic organ screening 6-9 months after mild to moderate SARS-CoV-2 infection is recommended to identify individuals at risk and initiate appropriate preventive therapies.
Source: Petersen, E., Goßling, A., Adam, G., Aepfelbacher, M., Behrendt, C., & Cavus, E. et al. (2022). Multi-organ assessment in mainly non-hospitalized individuals after SARS-CoV-2 infection: The Hamburg City Health Study COVID programme. European Heart Journal. doi: 10.1093/eurheartj/ehab914